major active constituent of silymarin

Active ingredient


Silybin is the principal active ingredient of silymarin. Silymarin is a standardized extract of the Milk thistle (Silybum Marianum) fruits, containing a mixture of flavonolignans, the most powerful of which is silybin. Milk thistle is also known as the Wild artichoke.

Silybin has an important role in liver protection and a strong antioxidant action, contributing to the detoxification process of the liver. Laboratory studies have shown that silybin stimulates the synthesis and the activity of enzymes important to detoxify the liver. Silybin is also known as an anti-hepatotoxic agent that inhibits the oxidative stress associated with alcohol, mushrooms and carbon tetrachloride consumption.

Silibină - Pentru ficat - HepatoDefense Capsule ProHumano+

Uses as natural remedy

Milk thistle is rich in beneficial substances such as beta-carotene, fumaric acid, silandrine, silibin, silicristin, silymarin, silydianin. It also contains many nutrients such as fatty acids, calcium, phosphorus, potassium, manganese, selenium and zinc.

Milk thistle consumptions is known to help the liver cleanse itself of accumulated toxins. Its seeds are edible, have a sweet taste and oily texture and can be eaten in salads or fresh juices. Milk thistle flowers are used to make tea. A higher concentration of silymarin is available when consuming milk thistle extract. The roots are frequently eaten raw as part of a salad platter or cooked.

Other names

Milk Thistle, Artichaut Sauvage, Blessed Milk Thistle, Cardo Lechoso, Cardui Mariae Fructus, Cardui Mariae Herba, Carduus Marianum, Carduus marianus, Chardon Argenté, Chardon de Notre-Dame, Chardon Marbré, Chardon-Marie, Épine Blanche, Holy Thistle, Lady's Thistle, Lait de Notre-Dame, Legalon, Marian Thistle, Mariendistel, Mary Thistle, Our Lady's Thistle, Silibinin, Silybe de Marie, Silybin, Silybum, St. Mary Thistle.

ProHumano+ products containing Silybin

HepatoDefense Capsule supports healthy liver function
ProHumano+ HepatoDefense Capsules helps liver protection and regeneration

Did you know?

Non-alcoholic Fatty Liver Disease is the most common chronic liver disease in children living in developed countries.

Liver disease
of teenagers

Information source:

Pediatric Nonalcoholic Fatty Liver Disease: Prevalence, Diagnosis, Risk Factors, and Management Stavra A. Xanthakos, Rohit Kohli- Clinical Liver Disease, Vol. 1, No. 4, August 2012, AASLD

Causes, symptoms and prevention methods for hepatic steatosis

The liver is the largest internal organ in the human body and the only visceral organ that has the ability to regenerate completely, to its previous size and capacity, without losing its functions during the growth process.

The liver is responsible for over 500 essential functions, the main ones being in the body’s metabolic processes. 

Read more »

Due to its many functions in the body, the liver plays a key role in maintaining general well-being and the joy for life.

Discover all active ingredients

Every ProHumano+ product encompasses the continuous care for people, down to the smallest detail.

HepatoDefense Capsule supports healthy liver function